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Showing posts with the label HER3

Lung Cancer Treatment Revolution: The Power of Antibody-Drug Conjugates

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  The ENHERTU Effect: A Closer Look at the Dynamic Duo Daiichi Sankyo and AstraZeneca Taking on HER2-mutant NSCLC Lung cancer remains one of the most challenging and prevalent forms of cancer. Within this landscape, innovative treatments are offering new hope. One such breakthrough is the collaboration between Daiichi Sankyo and AstraZeneca, which brings forth ENHERTU, an Antibody-Drug Conjugate (ADC). ENHERTU is making strides in targeting HER2-mutant Non-Small Cell Lung Cancer (NSCLC), a rare and challenging subset of the disease. The ENHERTU partnership aims to address this unmet medical need with a highly targeted approach. Dato-DXd vs. TRODELVY: The Battle of ADC Targeting TROP2 As the world of ADCs expands, another remarkable battle is brewing between Daiichi Sankyo's Dato-DXd and TRODELVY in their quest to target TROP2. TROP2, also known as CEACAM5, is an antigen overexpressed in various cancers, including endometrial cancer. Both ADCs hold the potential to transform the