6 Late-stage NASH Treatments Ready to Challenge REZDIFFRA’s Market Dominance
The Race for the Next Best NASH Drug Nonalcoholic Steatohepatitis (NASH) is a chronic liver disease with no FDA-approved treatments until recently, when Rezdiffra emerged as a frontrunner in NASH treatment. However, with a rising number of cases globally, the competition to dominate the NASH market is fierce. Numerous late-stage drugs in the NASH pipeline are challenging Rezdiffra's market dominance, each aiming to address the unmet medical needs of patients. 1. Resmetirom: Developed by Madrigal Pharmaceuticals, this thyroid hormone receptor-β agonist has shown potential to reduce liver fat, inflammation, and fibrosis in late-stage clinical trials. Resmetirom could significantly impact the NASH market size. 2. Lanifibranor: A pan-PPAR agonist developed by Inventiva, Lanifibranor is another promising candidate, currently in Phase III trials. It has demonstrated efficacy in reducing fibrosis and liver injury, making it a competitor to Rezdiffra in the Nonalcoholic Steatohepatitis