How will the recent developments help in the Chronic Pain Treatment Landscape?

 


What is Chronic Pain?

Chronic pain is a pain that lasts for more than three months. It can gradually grow and recur intermittently, outlasting the normal recovery process and adversely affecting the person’s well-being. Pain is supposed to cease after damaged tissue recovers until the root cause is treated.


The most common reason for adult impairment in the United States is chronic pain. There are currently 50 million Americans who have chronic pain. Lower back issues, arthritis, cancer, RSDS, repetitive stress disorders, shingles, headaches, and fibromyalgia are the most typical causes of chronic pain. Others include neurological disorders like phantom limb sensation and diabetic neuropathy. One of the most typical causes of chronic pain in people in their twenties is sports injuries. Every year, chronic pain costs society more than $100 billion.


Emgality (galcanezumab-gnlm), Aimovig (Eptinezumab), Tarlige (Mirogabalin besylate), Aimovig (Erenumab-aooe), Ajovy (Fremanezumab), Vyepti (Eptinezumab), and Pennsaid gel are just a few of the medications that have been approved for the treatment of chronic pain due to various indications.


Despite debates, opioids are thought to be the most effective drug for treating chronic pain. The purpose of managing chronic pain is to reduce symptoms and raise a person's level of functioning in daily activities. 

Musings on the chronic pain treatment 

The high prevalence of chronic pain among cancer patients is nothing new, but non-cancer people with a range of illnesses have also been found to experience chronic pain. It has been found that a significant portion of people with chronic pain experience osteoarthritis-related pain. Due to the disease's crippling effects on the cartilage between the joints, joints become excruciatingly painful.


Paradigm Biopharmaceuticals is creating ZILOSUL to fill the voids in the osteoarthritis treatment market. A semi-synthetic medication called pentosan polysulfate sodium (PPS) is made from the wood chips of European beech trees. The anti-inflammatory, tissue-regenerating, and somewhat anti-thrombotic effects of PPS activity are noteworthy.

In addition, a number of other industry titans, including AbbVie, Tonix Pharmaceuticals, Pfizer, Centrexion Therapeutics, Anika Therapeutics, Vertanical GmbH, Braeburn Pharmaceuticals, Grünenthal GmbH, Regeneron, Teva Pharmaceuticals, Biogen, and others, are looking into their respective candidates in a number of clinical trials for the treatment and management of chronic pain in the 7MM.


With new treatments like QULIPTA, TNX-102, reboxetine, CNTX-4975, CINGAL, dronabinol, buprenorphine, RTX-GRT7039, fasinumab, BIIB074, and others, the chronic pain pipeline appears to be promising.

The chronic pain treatment market is all set to grow significantly

The market landscape for treating chronic pain will change significantly over the forecast period as a result of the development of disease-specific chronic pain therapies. With better diagnosis and safe and effective chronic pain treatment options, the market for treating chronic pain is anticipated to increase dramatically.

However, there are two key concerns that affect the success of the new therapies in the chronic pain treatment market: difficulties with pricing and reimbursement, as well as related long-term side effects of approved medications.

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